Heart disease is increasingly affecting young adults, with a particularly concerning condition called diffuse coronary artery disease (CAD), where artery blockages are spread across multiple branches instead of a single location. Unlike standard blockages, diffuse CAD is harder to treat and can lead to more serious complications.
Dr Surinder Bazaz, senior director of cardiac surgery at Medanta – The Medicity, explains that in diffuse CAD, plaque builds up along the entire length of the arteries, often affecting multiple branches. This widespread narrowing restricts blood flow and makes treatment more complex. Unlike localized blockages, which can be treated with stents or bypass surgery, diffuse CAD often requires a combination of medical therapy, lifestyle modifications, and advanced surgical approaches in severe cases.
Symptoms often appear late, with early signs like mild chest discomfort, fatigue, or shortness of breath frequently ignored. By the time the condition is diagnosed, multiple arteries may already be involved.
Risk factors for young adults include:
- Lifestyle and diet – High stress, irregular sleep, lack of exercise, and diets rich in processed foods, refined carbs, and unhealthy fats contribute to early arterial damage. Fast food high in trans fats and sodium accelerates plaque buildup.
- Smoking and tobacco – Cigarettes and smokeless tobacco increase CAD risk by damaging artery linings and promoting inflammation.
- Metabolic disorders – Conditions such as diabetes, hypertension, and high cholesterol contribute to early arterial damage and diffuse plaque formation.
- Genetics – A family history of premature heart disease increases susceptibility, especially combined with lifestyle factors.
- Environmental factors – Exposure to toxins, pesticides, and unhealthy food additives may increase cardiovascular risks.
Prevention and management tips:
- Early screening for heart disease risk factors in individuals as young as their 20s.
- Lifestyle changes: Adopt a heart-healthy diet with fruits, vegetables, whole grains, and lean proteins, avoid processed and pesticide-laden foods, quit smoking, and maintain regular exercise.
- Medical therapy: Includes antiplatelet drugs, statins, beta-blockers, and medications to manage blood pressure and blood sugar.
- Interventional and surgical options: In select cases, drug-eluting stents, hybrid surgical approaches, endarterectomies, or total arterial grafting may be required.
- Monitoring and follow-up: Regular cardiac check-ups, lipid testing, and stress testing to track disease progression.
Early detection and lifestyle intervention are critical to reducing the risk of diffuse coronary artery disease and safeguarding long-term heart health in young adults.
