Artificial sweeteners are often promoted as healthier options for those trying to cut down on sugar intake, especially among people with diabetes. However, a recent study published in the Journal of Applied Physiology by scientists from the University of Colorado Boulder has raised serious health concerns regarding one such sweetener—erythritol.
Erythritol is widely used in sugar-free and low-calorie products and is present in well-known brands like Wholesome, Truvia, and Splenda. While it has been considered a safer alternative to sugar, the new research suggests that it may significantly elevate the risk of serious cardiovascular events, including strokes and heart attacks.
The team of researchers investigated the impact of erythritol on brain blood vessel cells. They exposed these cells to the level of erythritol commonly found in one sugar-free beverage. After treatment, the cells demonstrated reduced production of nitric oxide—a compound that supports the dilation of blood vessels. At the same time, they observed an increase in endothelin-1, a protein known to narrow blood vessels. These changes can increase blood pressure and restrict proper circulation.
Furthermore, the study revealed that erythritol exposure caused cells to release more free radicals. These unstable molecules are known to cause inflammation, promote cellular aging, and interfere with the body’s ability to dissolve blood clots. Even a single erythritol-rich drink was enough to trigger these changes at a cellular level.
Study author Auburn Berry explained, “If your blood vessels become narrower and your body’s capacity to eliminate blood clots declines, your likelihood of experiencing a stroke goes up.” Professor Christopher DeSouza further stated, “Considering both the epidemiological evidence and our latest cellular research, it is advisable to monitor and possibly limit the intake of non-nutrient sweeteners like erythritol.”
This research adds to a growing list of concerns surrounding artificial sweeteners and their long-term effects on human health. While these products may be marketed as guilt-free or healthy alternatives, consumers are encouraged to approach them with caution and consult healthcare professionals for personalized dietary advice.
Disclaimer: This article is intended for educational and informational purposes only. Please consult with a qualified healthcare provider regarding any health concerns or before making dietary changes.
